Microarray Analysis
The quality of the RNA is essential to the overall success of the gene expression analysis using microarray technology. Once you submit your samples, the Project Scientist will take an aliquot of your RNA sample and assess its quality. We will proceed with labeling process only when RNA is confirmed to be suitable.
Ribosomal RNA
Ribosomal RNA (rRNA) is the central component of the ribosome, the protein manufacturing machinery of all living cells. The function of the rRNA is to provide a mechanism for decoding mRNA into amino acids and to interact with the tRNAs during translation by providing peptidyl transferase activity. The ribosome is composed of two subunits, named for how rapidly they sediment when subject to centrifugation.
Eukaryotes
In contrast, eukaryotes generally have many copies of the rRNA genes organized in tandem repeats; in humans approximately 300–400 rDNA repeats are present in five clusters (on chromosomes 13, 14, 15, 21 and 22).The 18S rRNA in most eukaryotes is in the small ribosomal subunit, and the large subunit contains three rRNA species (the 5S, 5.8S and 28S rRNAs).
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Here you provide some information about Ribsomal RNA Services. It is designed to enrich the whole spectrum of RNA transcripts by selectively depleting ribosomal RNA molecules, regardless of their polyadenylation status or the presence of of a 5'-cap structure...
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