Monday, November 29, 2010

Peptide Drug Development


Bio-Synthesis, founded in 1984, is an international provider of genomic and proteomic services established around the core business lines oligonucleotide and peptide synthesis. We offer wide variety of peptide modifications and labelings from small discovery research scale to multi-gram ASR/cGMP for clinical diagnostic production. As always, quality is guaranteed!

Protein-Protein Interactions

The interactions between proteins are important for many biological functions. For example, signals from the exterior of a cell are mediated to the inside of that cell by protein-protein interactions of the signaling molecules. This process, called signal transduction, plays a fundamental role in many biological processes and in many diseases (e.g. cancer). Proteins might interact for a long time to form part of a protein complex, a protein may be carrying another protein (for example, from cytoplasm to nucleus or vice versa in the case of the nuclear pore importins), or a protein may interact briefly with another protein just to modify it (for example, a protein kinase will add a phosphate to a target protein).

Protein Sequencing

The first step is to determine the amino acid composition of the peptide. We provide high throughput automation with more precise and powerful protein analysis. The protein of interest having been purified and its mass determined, the next analysis usually performed is to determine the protein's amino acid sequence, or primary structure.

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