The availability of synthetic nucleic acids/oligonucleotides and peptides, areas where Bio Synthesis has extensive experience, has promoted the development of conjugates of these molecules cross-linked to compounds such as lipids, carbohydrates and small molecules (drugs) to yield products with distinct properties. Bio Synthesis has developed several approaches for the production of different bioconjugates. From the point of view of therapeutic applications, because of their potential uses in genetic therapy and blocking gene expression, the bioconjugates of nucleic acids are the most important ones. In general these bioconjugates acquire new properties, such as resistance to degradation and passage of the hydrophilic and anionic oligonucleotide across the hydrophobic negatively charged cell membrane or transduction. Yet, a suitable bioconjugate should maintain practically all of the oligonucleotide's biological properties.
Conjugation Services: - Oligonucleotide Peptide or protein conjugation
- Fluorescent labeling of peptide, proteins, drugs, DNA probes, etc.
- Protein-Protein conjugation
- Antibody conjugation
- Drug-Protein, peptide oliognucleotide conjugation
- Coupling of small molecules to carrier proteins
- Coupling of small molecules or proteins to solid support
- Chemical synthesis and modification of small molecules, proteins and drugs
Our team of experienced chemists is available to help our client arrive with the design and cross-linking strategies for the best approach to develop the optimal bioconjugates. As always, every custom project undergoes strict quality control - quality is always guaranteed! Quotations and Ordering: For quotations, you may also contact us by email , toll free (1.800.227.0627), oversea (972.420.8505), fax (1-972-420-0442), or via our secure online order/quote system.
Bio-Synthesis provides comprehensive custom antibody packages and immunological services, including epitope prediction, custom antibody synthesis
,carrier protein conjugation, immunization and purification, ELISA analysis, antibody labeling, and antibody microarrays. BSI offers peptide antigen design, using a proprietary Antigen Identifier TM design tool. Anti-peptide polyclonal antibody production is performed with the best titer guarantee in the industry, by implementing a proprietary SP-MaxTM adjuvant, a new family of adjuvants with improved properties, but minimal toxicity. BSI works with host animals under USDA license and holds an NIH Animal Welfare Assurance from the Office of Laboratory Animal Welfare for immunization. All procedures performed during immunization are described in our Standard Operation Procedures (SOPs) to ensure a high-quality product.
All custom polyclonal antibody projects are treated with strict confidentiality. Used animals, developed antigens remain the exclusive property of the customer.
From antigen selection to antibody purfication, BSI has optimized each step of the antibody production process to provided the best antibodies available.
We offer 8 standard custom antibody protocols (combinations of hosts and protocol timeframe) and 6 standard antibody packages (combinations of provisions, antigen and deliverables). For information about a particular protocol, see our Polyclonal Antibody Services below or request a quote today.
- Single anti-peptide polyclonal antibody
- Peptide phospho-specific polyclonal antibody
- Multiple-peptide co-immunization
- Multiple antigen peptide (MAP) polyclonal antibody
- User-supplied antigen
- Create-your-own antibody packages
Why choose Bio-Synthesis for your custom polyclonal antibody services?
Advanced antigen design- Proprietary Antigen Identifier design tool with team of expert scientist to assist client for best peptide antigen selection
- Supreme adjuvant SP-MAX technology
- A new family of adjuvants with improved properties, but minimal toxicity which ensures high specificity and titer of the produced antibodies.
- ELISA Guarantee
- Our polyclonal antibodies have an ELISA titer of 1:20,000 or better for any host if peptide antigens were designed, synthesized, and conjugated by Bio-Synthesis.
Comprehensive antibody packages
- Single anti-peptide polyclonal antibody
- Peptide phospho-specific polyclonal antibody
- Multiple-peptide co-immunization
- Multiple antigen peptide (MAP) polyclonal antibody
- User-supplied antigen
- Create-your-own antibody packages
Conjugation Services: 
