Tuesday, January 11, 2011

FITC Excitation


Bio-Synthesis offers a complete array of luorescent reporters and quenchers to our custom oligonucleotides, peptides and antibodies. Our product offereing includes common dye modifiers such as 6-FAM, HEX and TET, as well as exotic modifictions.

Fluorescein Isothiocyanate

Fluorescein isothiocyanate (FITC) is a derivative of fluorescein used in wide-ranging applications including flow cytometry. FITC is the original fluorescein molecule functionalized with an isothiocyanate reactive group (-N=C=S), replacing a hydrogen atom on the bottom ring of the structure. This derivative is reactive towards nucleophiles including amine and sulfhydryl groups on proteins.

Genetic Testing

Genetic testing allows the genetic diagnosis of vulnerabilities to inherited diseases, and can also be used to determine a person's ancestry. Normally, every person carries two copies of every gene, one inherited from their mother, one inherited from their father. Genetic testing identifies changes in chromosomes, genes, or proteins.

DNA Test

A genealogical DNA test examines the nucleotides at specific locations on a person's DNA for genetic genealogy purposes. The test results are meant to have no informative medical value and do not determine specific genetic diseases or disorders (see possible exceptions in Medical information below); they are intended only to give genealogical information.

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