Custom Plasmid

Custom Plasmid

A plasmid is an extra-chromosomal DNA molecule separate from the chromosomal DNA which is capable of replicating independently of the chromosomal DNA.In many cases; it is circular and double-stranded. Plasmids usually occur naturally in bacteria, but are sometimes found in eukaryotic organisms.

Gene Therapy

The success of gene therapy depends on the efficient insertion of therapeutic genes at the appropriate chromosomal target sites within the human genome, without causing cell injury, oncogenic mutations or an immune response. Plasmid vectors could be used for this purpose. Zinc finger nucleases (ZFNs) offer a way to cause a site-specific double strand break to the DNA genome and cause homologous recombination.

Ti Plasmid

Ti plasmid is a circular plasmid that often, but not always, is a part of the genetic equipment that Agrobacterium tumefactions and Agro bacterium rhizogenes use to transducer its genetic material to plants.