Catalog# : 5223
KLHL15 is a member of a growing superfamily of kelch repeat-containing proteins. The kelch motif was discovered in the sequence of the Drosophila kelch ORF1 protein and forms a conserved beta-propeller tertiary structure. These kelch-like proteins have been implicated in embryogenesis and carcinogenesis through cytoskeleton organization. KLHL15 mRNA is widely expressed in many tissues and is thought to be involved in protein ubiquination and cytoskeleton organization.
Additional Names : KLHL15, Kelch-like 15 protein
DescriptionLeft: Western blot analysis of KLHL15 in HeLa cell lysate with KLHL15 antibody at (A) 1 and (B) 2 µg/ml.
Below: Immunocytochemistry of KLHL15 in HeLa cells with KLHL15 antibody at 5 μg/ml.
Other Product Images
Source : KLHL15 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KLHL15.Purification : Affinity chromatography purified via peptide column
Clonality and Clone : This is a polyclonal antibody.
Host : KLHL15 antibody was raised in rabbit. Please use anti-rabbit secondary antibodies.
Application : KLHL15 antibody can be used for detection of KLHL15 by Western blot at 1 - 2 µg/ml.
Tested Application(s) : E, WB
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide : Cat.No. 5223P - KLHL15 Peptide
Long-Term Storage : KLHL15 antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control
1. Cat. No. 1201 - HeLa Cell Lysate
Species Reactivity :H, M, R
GI Number : 226442729
Accession Number : NP_085127
Short Description : Kelch-like 15 protein
References
1. Yoshida K. Identification and characterization of a novel kelch-like gene KLHL15 in silico. Oncol. Rep. 2005; 13:1133-7.
2. Robinson DN and Cooley L. Drosophila kelch is an oligomeric ring canal actin organizer. J. Cell Biol. 1997; 138:799-810.
3. Adams J, Kelso R, and Cooley L. The kelch repeat superfamily of proteins: propellers of cell function. Trends Cell Biol. 2000; 10:17-24.
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