Catalog# :5261
Ankyrin (ANK) repeats mediate protein-protein interactions in diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20. ANK repeats may occur in combinations with other types of domains. The structural repeat unit contains two anti-parallel helices and a beta-hairpin, with repeats stacked in a superhelical arrangement. LIAR, also known as ANKRD54, is a recently identified ANK repeat-containing protein that is predominantly expressed in tissues rich in cilliated cells, such as olfactory sensory neurons and is predicted to be important to cilia. At least three isoforms of LIAR are known to exist.
Additional Names : LIAR, Lyn-interacting ankyrin repeat protein, ankyrin repeat domain 54, ANKRD54
DescriptionLeft: Western blot analysis of LIAR in mouse kidney tissue lysate with LIAR antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
Below: Immunohistochemistry of LIAR in mouse kidney tissue with LIAR antibody at 2.5 μg/ml.
Other Product Images
Source :LIAR antibody was raised against a 16 amino acid peptide near the carboxy terminus of human LIAR.Purification : Affinity chromatography purified via peptide column
Clonality and Clone : This is a polyclonal antibody.
Host : LIAR antibody was raised in rabbit. Please use anti-rabbit secondary antibodies.
Application : LIAR antibody can be used for detection of LIAR by Western blot at 1 - 2 µg/ml.
Tested Application(s) : E, WB
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide :Cat.No. 5261P - LIAR Peptide
Long-Term Storage : LIAR antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control :
1. Cat. No. 1405 - Mouse Kidney Tissue Lysate
Species Reactivity : H, M, R
GI Number : 20270347
Accession Number : NP_620152
Short Description : Ankyrin repeat domain 54
References
1. Li J, Mahajan A, and Tsai MD. Ankyrin repeat: a unique motif mediating protein-protein interactions. Biochemistry 2006; 45:15168-78.
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