Tuesday, February 15, 2011

ZBTB1 Antibody

ZBTB1 Antibody

Catalog# :4951

ZBTB1 is a zinc finger protein that also contains BTB (BR-C, ttk and bab) domain. While little is known about this protein or the related protein ZBTB2, its expression is known to be down-regulated in human bronchial epithelial cells in response to the presence of Vanadium. Recently, expression of variant ZBTB1 protein has been associated with increased age-related macular degeneration. At least two isoforms of ZBTB1 are known to exist. This ZBTB1 antibody will not cross-react with ZBTB2.

Additional Names : ZBTB1, Zinc finger and BTB domain-containing protein 1, ZBTB

Left:Western blot analysis of ZBTB1 in HepG2 lysate with ZBTB1 antibody at (A) 1 and (B) 2 µg/ml.

Below Immunohistochemistry of ZBTB1 in mouse brain tissue with ZBTB1 antibody at 2.5 µg/ml.

Other Product Images

Source :ZBTB1 antibody was raised against a 14 amino acid peptide near the center of human ZBTB1.
Purification : Affinity chromatography purified via peptide column
Clonality and Clone : This is a polyclonal antibody.
Host : ZBTB1 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application : ZBTB1 antibody can be used for detection of ZBTB1 by Western blot at 1 – 2 µg/ml.
Tested Application(s) : E, WB, IHC
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide :Cat.No. 4951P - ZBTB1 Peptide
Long-Term Storage : ZBTB1 antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control :
1. Cat. No. 1211 - HepG2 Cell Lysate
Species Reactivity : H, M, R
GI Number : 29792103
Accession Number : AAH50719
Short Description : Zinc finger and BTB domain-containing protein 1
1. Strausberg RL, Feingold EA, Grouse LH, et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. USA 2002; 99:16899-903.
2. Li Z, Stonehuerner J, Devlin RB, et al. Discrimination of Vanadium from Zinc using gene profiling in human bronchial epithelial cells. Envir. Health Perspect. 2005; 113:1747-54.
3. Zhang H, Morrison MA, Dewan A, et al. The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration. BMC Med. Genet. 2008; 9:51.

No comments: