Sunday, March 20, 2011
Biosyn can provide RNA, RNA analogs and chimeras in large quantities for your diagnostic and therapeutic research. Biosyn continues the tradition of providing researchers with the highest quality RNA Oligonucleotide synthesis, in quantities ranging from multi-mg to several grams.
RNA Oligonucleotide Synthesis
Oligonucleotide synthesis is the non-biological, chemical synthesis of defined short sequences of nucleic acids. It is extremely useful in laboratory procedures covering a wide range of molecular biology applications. Automated synthesizers allow the synthesis of oligonucleotides up to 200 bases even longer.
RNA hybrid is a double-stranded polynucleic acids in which one strand is DNA and the other strand is the complementary RNA; formed during transcription and during multiplication of oncogenic RNA viruses.This form is also assumed by DNA-RNA hybrid helices and by regions of double-stranded RNA. It is a right-handed helix and is a more compact form than beta-DNA.
RNA Interference (RNAi)
RNA interference (RNAi) by double stranded RNA (dsRNAs) molecules of approximately 20-25 nucleotides termed short interfering (siRNAs) is a powerful method for preventing the expression of a particular gene. The dsRNA dominantly silences gene expression in a sequence-specific manner by causing the corresponding endogenous mRNA to be degraded.