Wednesday, May 11, 2011

DNA-Binding Proteins

Bio-Synthesis, founded in 1984, is an international provider of genomic services established around the core business lines oligonucleotide and gene synthesis. Base, ribose and backbone modifications and reporter groups like dyes and haptens are routinely incorporated in DNA/RNA hybrid synthesis. Through innovative production process and synthesis know-how, our services are the best in their class, providing you with innovative and trustworthy solutions to accelerate your research.

DNA Binding Proteins

DNA-binding proteins include transcription factors which modulate the process of transcription, nucleases which cleave DNA molecules, and histones which are involved in DNA packaging in the cell nucleus. DNA-binding proteins can incorporate such DNA-binding domains as the zinc finger, the helix-turn-helix, and the leucine zipper (among many others).

Single Strand Binding Protein

Single-strand binding protein, also known as SSB or SSBP, binds single stranded regions of DNA to prevent premature reannealing. The strands have a natural tendency to revert to the duplex form, but SSB binds to the single strands, keeping them separate and allowing the DNA replication machinery to perform its function.


A protein is a complex, high molecular weight organic compound that consists of amino acids joined by peptide bonds. Organize articles about proteins according to a standard protein ontology.

1 comment:

Ubiquitin Antibody said...

Hi all,

DNA-binding proteins are proteins that are composed of DNA-binding domains and thus have a specific or general affinity for either single or double stranded DNA. Sequence-specific DNA-binding proteins generally interact with the major groove of B-DNA, because it exposes more functional groups that identify a base pair. Thanks a lot!