Wednesday, May 25, 2011

HIV Epitope

For over 20 years, BioSynthesis has provided custom peptide production services and stock HIV peptides. Our unique and comprehensive experience has enable us in providing chemically synthesized peptides ranging from highly challenging ultra-pure peptidomimetics and long peptides to complex peptide libraries consisting of thousands of fully characterized peptides to highly regulated multiple kilogram per batch GMP peptides. Our goal is to be your single peptide partner at every stage in the peptide drug development continuum from design of peptide libraries, through to GMP manufacturing of active pharmaceutical ingredients (APIs) and commercialization. Our consistency, viability, and delivery are guaranteed.


An Epitope is the part of a macromolecule that is recognized by the immune system, specifically by antibodies, or T cells. Although epitope are usually thought to be derived from non self proteins, sequences derived from the host that can be recognized are also classified as epitope.

Epitope Mapping

It is the process of matching surface proteins to antibodies that will bond to them. Epitope mapping is the process of identification and characterization of the minimum molecular structures that are able to be recognized by the Immune System elements, mainly T and B cells. A collection of in vivo and in vitro methodologies are used for epitope mapping.


Antibodies (also known as immunoglobulins are proteins that are found in blood or other bodily fluids of vertebrates, and are used by the immune system to identify and neutralize foreign objects, such as bacteria and viruses.

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