Secretory carrier membrane proteins (SCAMPs) are integral membrane proteins seen in secretory and endocytic carriers that are thought to play roles in membrane trafficking. One member of this family, SCAMP4, lacks the putative calcium binding and leucine zipper structures as well as the protein-protein interacting NPF domains common to most SCAMP family members. In rats, SCAMP4 mRNA is repressed by progesterone in brain regions associated with female sexual behavior. At least three isoforms of SCAMP4 are known to exist. This SCAMP4 antibody is predicted to not cross-react with any other member of the secretory carrier membrane protein family.
Additional Names : SCAMP4, Secretory carrier membrane protein 4
Left: Western blot analysis of SCAMP4 in 3T3 cell lysate with SCAMP4 antibody at (A) 1 and (B) 2 µg/ml.
Below:Immunohistochemistry of SCAMP4 in human brain tissue with SCAMP4 antibody at 2.5 μg/ml.
Other Product Images
Source :SCAMP4 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SCAMP4.
Purification : Affinity chromatography purified via peptide column
Clonality and Clone : Polyclonal
Host : SCAMP4 antibody was raised in rabbit.
Please use anti-rabbit secondary antibodies.
Application : SCAMP4 antibody can be used for detection of SCAMP4 by Western blot at 1 - 2 µg/ml.
Tested Application(s) : E, WB, IHC
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide :Cat.No. 5289P - SCAMP4 Peptide
Long-Term Storage : SCAMP4 antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Positive Control :
1. Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Species Reactivity : H, M, R
GI Number : 17738287
Accession Number : NP_524558
Short Description : Secretory carrier membrane protein 4
1. Hubbard C, Singleton D, Rauch M, et al. The secretory carrier membrane protein family: structure and membrane topology. Mol. Biol. Cell 2000; 11:2933-47.
2. Krebs CJ and Pfaff DW. Expression of the SCAMP-4 gene, a new member of the secretory carrier membrane protein family, is repressed by progesterone in brain regions associated with female sexual behavior. Brain Res. Mol. Brain Res. 2001; 88:144-54.