Wednesday, May 4, 2011
Biosyn Serving molecular diagnostic community since 1984. It provides great resource of RNA Research Analysis, RNA catalysis and RNA processing. We are providing comprehensive Custom RNA synthesis and modification such as RNA Chimeras and RNA Conjugations. From RNA probe selection to chemical synthesis. Our team of molecular biologists is dedicated in serving clients for their RNA research.
Research leading to the discovery that RNA can act as a catalyst started in the 1970’s. Thomas Cech, at the University of Colorado at Boulder, was studying the excision of introns in a ribosomal RNA gene in Tetrahymena thermophila.
DNA (deoxyribonucleic acid) makes RNA (ribonucleic acid) makes protein—has been established since the 1960s. The famous double helix of DNA is the cell's permanent storehouse of information. RNA transmits this information to the protein synthesis machinery, producing DNA-encoded protein.
A synthetic RNA catalyst capable of cleaving an RNA substrate, the catalyst comprising a substrate binding portion and a "hairpin" portion. The invention also provides an engineered DNA molecule and a vector, each comprising a DNA sequence coding for an RNA catalyst according to the invention.