Monday, September 20, 2010

Multiple Antigen Peptide Conjugation System

BIO-SYNTHESIS offers MAPS as an another method for producing high titer anti-peptide antibodies. This newer concept was introduced to avoid chemically undefined entity of an antigen-carrier system. The MAP system utilizes a peptidyl core of three or seven radially branched lysine core to form a backbone for which the antigen sequences of interest can be built parallel using standard solid-phase chemistry. The heptalysine core yields the MAP bearing four or eight copies of the peptide epitope with a resulting three dimensional molecule which has a high molar ratio of peptide antigen to core molecule, and therefore, does not require the use of a carrier protein to induce an antibody response. These high molar ratio and dense packing of multiple copies of the antigenic epitope in a MAP has been shown to produce strong immunogenic response.

For details on Multiple Antigen Peptide (MAPS), call 800-227-0627 or write to us at

Service Features:
  • Synthesis up to 10 residues
  • Immunization of 2 rabbits
  • ELISA testing on all bleeds
  • 100-150 mls of crude serum
  • 10-12 weeks delivery
  • QC peptide by HPLC and mass spectrometry
  • 5 mgs MAP delivered to customer

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