Catalog# : 4987
OCC-1 (Overexpressed in colon carcinoma-1) was initially identified as a novel human cDNA overexpressed in a colon carcinoma cell line. Elevated levels of OCC-1 mRNA were observed in three of eight colon carcinomas, suggesting that OCC-1 may be a hallmark of only a subset of colon carcinomas. It is highly expressed in skeletal muscle, kidney, placenta, and pancreas tissues, with low to no expression in heart, brain, lung and liver tissues. At least two different OCC-1 mRNA species are known to exist. In vitro transcription and translation of the OCC-1 cDNA yields polypeptides less than 9 kDa. Despite this, OCC-1 from cell lines is detected at ~28 kDa in SDS-PAGE.
Additional Names : OCC-1 (CT), Overexpressed in colon carcinoma-1
Left: Western blot analysis of OCC-1 in 293 cell lysate with OCC-1 antibody at (A) 2 µg/ml and (B) 4 µg/ml.
Below: Immunohistochemistry of OCC-1 in human spleen tissue with OCC-1 antibody at 2.5 µg/ml.
Other Product Images
Source : OCC-1 antibody was raised against a 7 amino acid peptide near the carboxy terminus of human OCC-1.
Purification : Affinity chromatography purified via peptide column
Clonality and Clone : This is a polyclonal antibody.
Host : OCC-1 antibody was raised in rabbit. Please use anti-rabbit secondary antibodies.
Application : OCC-1 antibody can be used for detection of OCC-1 by Western blot at 2 – 4 µg/ml.
Tested Application(s) : E, WB, IHC
Buffer : Antibody is supplied in PBS containing 0.02% sodium azide.
Blocking Peptide : Cat.No. 4987P - OCC-1 Peptide
Long-Term Storage : OCC-1 antibody can be stored at 4ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
1. Cat. No. 1210 - 293 Cell Lysate
Species Reactivity :H
GI Number : 112180576
Accession Number : AAH61920
Short Description : (CT) Overexpressed in colon carcinoma-1
1. Pibouin L, Villaudy J, Ferbus D, et al. Cloning of the mRNA of overexpression in colon-carcinoma-1: a sequence overexpressed in a subset of colon carcinomas. Cancer Genet. Cytogenet. 2002; 133:55-60.